Proactol vs Xenical comparison

Lately we have spotted 2 diet pills that have similar mechanism of action – Xenical and Proactol. One of them is prescription only and the other one is over the counter. Now we wanted to put them side by side and see which one of these diet pills is better and safer in the long run.

What is Proactol?

Proactol is non-prescription 100% herbal fat binding diet pill that can bind about 28% of the fats from the food that you eat and make them indigestible. Those undigested fats are then eliminated naturally from your body.

NeOpuntia is the name of the main ingredient inside Proactol. This fibre complex is derived from nutritious cactus Opuntia Ficus Indica, proven to contain great fat binding properties. Other than this Proactol has 3 medical studies done on it and all users can see those studies on the official Proactol website. This fat binder is assessed under Medical Device Directive 93/42/EEC in European Union.

What is Xenical?

Xenical is prescription only weight loss drug that contains Orlistat as its main ingredient. Xenical is believed to work by acting as a natural lipase inhibitor, stopping about 1/3 of the fats from your diet this way. Some studies in the past suggested that using Xenical for up to a year resulted in losing more than 10% of the initial body weight.

Since both Proactol and Xenical are recognized worldwide as being successful fat binders, these supplements at first seemed to match each other’s benefits one by one. They both helped numerous users lose 1-2 lbs/week while at the same time offering other health benefits such as lowering blood cholesterol levels, high energy levels and such.

However, after a closer examination of both supplements we noticed what possible could be the key factor in deciding which supplement to buy: Xenical had numerous side effects!

Don’t get us wrong – Xenical for sure has a lot to offer. Xenical is even proven to help you decrease your fat intake by 2% more than Proactol, however this additional benefit comes with big price tag attached to it.

According to one study, about 91% of Xenical users who lost weight with it experienced some form of side effects with this drug. Even on the official website of Xenical they warn about possible side effects that are likely to arise.

The most common side effects to appear with Xenical are: oily rectal discharge, passing gas with oily discharge, oily or fatty stools, immediate need to have bowel movement, increased number of bowel movements and being unable to control your bowel movements. Xenical can also cause some rather serious side effects such as: inability of body to absorb certain vitamins, liver problems, kidney problems, and gallbladder problems.

There are some rather embarrassing side effects with Xenical, you would agree.

Comparison table

Proactol Xenical
Type Fat binder Fat binder
Effectiveness Binds up to 28% of the fats from your diet Binds about 1/3 of the fats from your diet
Ingredients NeOpuntia (100% natural) Orlistat (synthetic)
Medical approval

3 clinical studies

Several doctors endorsing it

Medical Device Directive 93/42/EEC

XENDOS study
Side effects None Headache



Flatulence with discharge

Oily/fatty stools

Rectal bleeding

Infections of airways

Urinary tract infection

irregular menstrual cycle

Gall stones

Increased bowel movement

Requires prescription? No Yes
Can be used for

as long as you want?

Xenical or Proactol? Which one is safer in the long run?

When we place Proactol next to Xenical we have to admit that Proactol wins this battle any time of the day. Reliable, credible and without any side effects, Proactol is definitely the superior diet pill in this case.

With Proactol there is no time limit to how long users can use it. While Xenical is only for certain people (BMI 30+), Proactol can be used by either dieters who want to shed just a few pounds or by dieters who need to lose large amounts of weight.

And we’re not claiming that Xenical isn’t effective. On the contrary; it has helped a lot people lose weight, however the main problem are side effects that are almost guaranteed to appear with Xenical. When we’re recommending supplements, our primary concern is safety, and Proactol is definitely safer supplement in our opinion (no side effects).

Proactol – our top recommendation

If you are looking for safe natural weight loss aid that doesn’t cause any side effects and can be used in the long run, then we fully recommend Proactol. This diet pill has been on the market since 2007 and comes from reputable manufacturers that obviously know what they are doing.

Visit official Proactol website for more details


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